林岩,朱晓亮,李汛
LIN Yan,ZHU Xiao-liang,LI Xun

• 1:兰州大学第一临床医学院
• 2:兰州大学第一医院普外科

摘要(Abstract)：

胆管狭窄是肝移植术后常见并发症之一,是移植受体病残和死亡的重要原因。根据狭窄发生部位不同,肝移植术后胆管狭窄可分为吻合口狭窄和非吻合口狭窄。内镜下治疗是胆管端-端吻合口狭窄的首选方式。既往内镜治疗肝移植术后胆管狭窄主要通过球囊扩张和单根或多根塑料支架置入。随着新型支架、先进内镜设备及对接技术、磁压缩吻合技术等新型治疗技术的发展,肝移植术后胆管狭窄的治疗取得进一步进展。本文就肝移植术后胆管狭窄的发生与分类、原因和危险因素、临床表现、诊断及治疗的研究进展作一综述。
Biliary stricture is one of the most common complications after liver transplantation,and an important cause of morbidity and mortality in transplant recipients.Bile duct stricture after liver transplantation is divided into anastomotic stricture and non-anastomotic stricture according to the stricture site.The endoscopic approach is currently the preferred initial treatment method for patients undergoing duct-to-duct biliary reconstruction.Previously,endoscopic management used to rely on balloon dilatation and single or multiple stents placement.Recently,agreat progress has been achieved by the application of endoscopic devices and novel biliary stents,as well as the advances in endoscopic technologies including the rendezvous technique and magnetic compression anastomosis.This paper reviews the research progress of the occurrence,classification,cause,risk factor,clinical manifestation,diagnosis and treatment of bile duct stricture after liver transplantation.

关键词(KeyWords)： 肝移植;胆管狭窄;内镜治疗
Liver transplantation;biliary stricture;endoscopic management

Abstract:

Keywords:

基金项目(Foundation): 甘肃省科技重大专项项目(1602FKDA001);; 兰州市人才创新创业科技计划项目(2016-RC-57)

作者(Author): 林岩,朱晓亮,李汛
LIN Yan,ZHU Xiao-liang,LI Xun

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